PREMARIN HORSES — Virgina Hopkins M.A. writes in an article entitled, “The Definition of Bio-identical Drugs“:
Bio-identical hormones may be either from a natural source or synthetically made, and it’s more about the molecule being identical to the human molecule that our body normally makes, than whether it comes from a natural source.
With the exception of Premarin, which is extracted from the urine of pregnant mares, virtually all replacement and contraceptive hormones, in all forms, bio-identical or synthetic, are first extracted from soybeans or wild yams in a laboratory.
Those that are processed so that they exactly match the molecular structure of the hormones made by the human body have come to be called bio-identical, to distinguish them from synthetic hormones, which have a molecular structure that is not found in nature, and certainly not in the human body.
That Ms. Hopkins makes a distinction between Premarin® and other drugs used to treat menopausal and post-menopausal symptoms is an important one.

Some doctors are still telling patients that Premarin® drugs are no longer made with conjugated equine estrogens, but simply conjugated estrogens. These doctors are confused about this because that is how the FDA allows Pfizer to label these drugs on their packaging.
Conjugated estrogens can be made from plants.
Clearly. Premarin® drugs are made from pregnant mare’s urine and contain conjugated equine estrogens.
Beware. The World Health Organization has designated conjugated equine estrogens as known carcinogens.
RxList.com uses the phrase conjugated estrogens when referencing Premarin® drugs. However, if you look far enough on their website, you finally arrive at the drug’s description which makes the following statements:
Premarin® is a “mixture of conjugated estrogens purified from pregnant mares’ urine and consists of the sodium salts of water-soluble estrogen sulfates blended to represent the average composition of material derived from pregnant mares’ urine. It is a mixture of sodium estrone sulfate and sodium equilin sulfate. See http://www.rxlist.com/premarin-drug.htm.
Is you scroll up just above “Drug Description”, there is grey box with a list of side effects. The title sums it up. In all caps, bold letters it says:
WARNING
ENDOMETRIAL CANCER, CARDIOVASCULAR DISORDERS, BREAST CANCER AND PROBABLE DEMENTIA
Say No to Premarin® Drugs
Premarin® is prescribed in two forms — cream and tablet.
Premarin® is also used in others ways that you may never be made aware of, for example, during surgery to act as a coagulent in cases of heavy bleeding. Tell you doctor you wish never to be treated with any of the Premarin® family of drugs.
Premarin Horse Resources
As Jane Allin states, “Nothing has been, or ever will be, appealing or beneficial about the PMU industry and the Premarin family of drugs; they are clearly harbingers of death from both sides of the equation”.
Read more articles on this subject here at Tuesday’s Horse.
If you see an ad for Premarin® drugs, cream or tablet, make a note of where and when and please let us know. Thank you.
Read Jane Allin’s Special Reports on Premarin® drugs on our website.
Learn more about the mares used to make Premarin® drugs and what happens to their foals at Premstoppers on our website.
IMAGE CREDITS
Belgian Foal — Photographer unknown.
Premarin® tablets packaging — Drugsnow.com.
Do you know what the synthetic hormones are for menopausal women? Im struggling with symptoms but have stayed away from hormones due to utilization of pregnant mares.
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I have been searching over many months for the real names of HRT drugs (either bioidential or synthetic) that are as effective as Premarin but are NOT involved with the PMU industry. This information across the web seems incomplete, overly complicated, and unclear. Also some of the medical sites have doctors flat out saying that bioidentials just don’t work or are unsafe. No one as far as I can see, has created a chart that is understandable and complete. Does this mean that in reality, there is nothing out there as effective as Premarin products?
I try to educate my woman friends but if there is truly no non-abusive alternative I can suggest, how can I expect them to change?
Trust me, the doctors are NOT educated in the abusive nature of the PMU industry and a lot of them just don’t care and will offer NO alternatives. You can ask for a non-Premarin substitute but they look at you as if you’re crazy.
Could someone please direct us to, or create an comprehensive, understandable, complete chart of what is available (and what works!) as alternatives?
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