Three things we are doing for Premarin horses

Rescued Premarin foals. Photo: Vivian Grant Farrell.
Rescued Premarin foals. Photo: Vivian Grant Farrell.

Here are three things we are doing for PMU — or Premarin — horses right now:

1. Lobbying the FDA with the help of a specialist firm to return the word “equine” on all Premarin type drugs so it reads “conjugated equine estrogens” the way it did, and should*.

2. Working in China with a massive social media campaign warning women against the dangers of the Premarin family of drugs. This is where most of the horses are and where the largest volume of Premarin type drugs are being used. 

3. Leafleting across the U.S. at women’s hospitals and clinics warning women about the dangers of the Premarin family of drugs and educating them on alternatives (expanding into Canada with your help).

This work is informative and necessary, and potentially life saving for women and the mares and foals used to make the drug then cast off.


Make a donation now in support of this critical work.
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We are the only voices PMU horses have. When we remove the demand for these drugs we remove the demand for pregnant mare’s urine thereby freeing the horses.

Share this with the women in your life and anyone else who might be exposed to this drug.

Helpful Links

Alternatives to Premarin®.

Premstoppers campaign page at The Horse Fund website.

Donate to Premstoppers.

Thank you for your caring support of women and horses.


* A conjugated estrogen can be made from plants.

Premarin, doctors and conjugated equine estrogens

March for Premarin Horses featured image.
The Premarin family of HRT drugs is made from the urine of pregnant mares.

Updated: 1:50 pm

MORE and more doctors who prescribe Premarin® are arguing with us that the menopausal drug no longer contains conjugated equine estrogens derived from pregnant mare’s urine. Huh?

The idea doctors most often cite in support of this belief is what it says on the drugs’ packaging, that Premarin® is made from “conjugated estrogens” where it used to say “conjugated equine estrogens”. Removing the word equine is something Pfizer pressed the FDA to do shortly we believe after they merged with or acquired Wyeth pharamaceuticals, adding these drugs to their portfolio. The removal of the word equine is obviously having its desired effect.

Premarin sample package with words "conjugated estrogens". Google search result. Unattributed image.
Premarin sample package with words “conjugated estrogens”. Google search result. Unattributed image.

Well dear doctors. A quick check on the internet should assure you that the Premarin® family of drugs including Duavee (originally called Aprela) which we don’t hear much of, has and assuredly always will be made with CEE’s — conjugated equine estrogens.

Wikipedia

Conjugated estrogens (CEs), or conjugated equine estrogens (CEEs), sold under the brand name Premarin (a contraction of “pregnant mares’ urine”) among others, is an estrogen medication which is used in menopausal hormone therapy and for various other indications. Read more »

RxList

PREMARIN® (conjugated estrogens tablets, USP) for oral administration contains a mixture of conjugated estrogens purified from pregnant mares’ urine and consists of the sodium salts of water-soluble estrogen sulfates blended to represent the average composition of material derived from pregnant mares’ urine. Be sure to check out the side effects. They include endometrial cancer, cardiovascular disorders, breast cancer and probably dementia. Read more »

DrugBank

Conjugated Equine Estrogens (CEEs) are derived from the urine of pregnant mares and contain a blend of at least 10 estrogen derivatives. Marketed under the brand name Premarin, CEEs are the most frequently used form of conjugated estrogens.

All estrogen products mimic the effects of endogenous estrogens in the body which are responsible for the development and maintenance of the female reproductive system and secondary sexual characteristics.

Conjugated estrogens, or Conjugated Equine Estrogens (CEEs) are composed of a mixture of the water-soluble salts of sulfate esters from estrone, equilin, 17 α-dihydroequilin, and other related steroids that are purified from pregnant horse urine. Available as the product Premarin (FDA), this combination of equine-derived estrogenic compounds is indicated for the following conditions: treatment of moderate to severe vasomotor symptoms and vulvovaginal atrophy associated with menopause; hypoestrogenism due to hypogonadism, castration or primary ovarian failure; palliation of metastatic breast cancer; palliation of advanced androgen-dependent carcinoma of the prostate; and for prevention of postmenopausal osteoporosis. Read more »

PubChem

Premarin is a pharmaceutical preparation containing a mixture of water-soluble, conjugated estrogens derived wholly or in part from URINE of pregnant mares or synthetically from ESTRONE and EQUILIN. It contains a sodium-salt mixture of estrone sulfate (52-62%) and equilin sulfate (22-30%) with a total of the two between 80-88%. Other concomitant conjugates include 17-alpha-dihydroequilin, 17-alpha-estradiol, and 17-beta-dihydroequilin. The potency of the preparation is expressed in terms of an equivalent quantity of sodium estrone sulfate. Read more »

See also NCBI » See also MedScape for Black Box Warnings such as increased risk of invasive breast cancer »

We get the picture. Surely doctors will now too.

Take Action

Dear Doctor Letter

Print and mail this letter to your doctor.

• PREMARIN_Dear_Doctor_Letter_UPDATED_October_2018_WORD (pdf, 4 pp)

Send this letter whether you are male or female. Doctors are known to use Premarin® intervenously to prevent bleeding during surgery.  So you may be treated with Premarin® without even knowing it or giving your permission. More to come on that so stay tuned here.

In the meantime, share far and wide. Save the horses!

China

The biggest challenge outside of the US is educating the Chinese who produce more pregnant mare’s urine and prescribe it more than anyone else in the world according to a recent source in China. And the Chinese love horse meat. So the two — Premarin® and horse slaughter — continues to go hand in hand.

Premarin tables. If you look closely you can see a legend in Chinese. Google image.
Premarin tables. If you look closely you can see a legend in Chinese. Google image.
Chinese version of Premarin cream.
Chinese version of Premarin cream.

In the meantime, doctors in the US are still prescribing and using the Premarin® family drugs at an alarming rate and seemingly unaware of the history and multiple dangers associated with this despicable drug.


Nothing has been, or ever will be, appealing or beneficial about the PMU industry and the Premarin family of drugs; they are clearly harbingers of death from both sides of the equation”.
– JANE ALLIN


Related Reading

•  Update! Alternatives to drugs made with pregnant mare’s urine by Jane Allin »

A look at a PMU farm in China and its not all about Pfizer »

Premstoppers

Premstoppers  is a Horse Fund campaign to eliminate drugs made with pregnant mare’s urine and their decades old legacy of cruelty and death.

Learn more at the Horse Fund website »

Donate

Donate to Premstoppers »

Thank you!

U.S. Agribusiness lobbying hard for return of horse slaughter

Fund Horse, US Flag and Capitol Dome. Vivian Grant Farrell.
Fund Horse, US Flag and Capitol Dome. Vivian Grant Farrell.
Fund Horse, US Flag and Capitol Dome. Vivian Grant Farrell. Click image to join the Horse on the Hill™ Gang.

WASHINGTON, D.C. — Meat peddlers in the U.S. are happy. Why? In a word. China.

While trying to put together some statistics on U.S. meat production and consumption during Meat Out for Mustangs, a meat man made this remark to Tuesday’s Horse, “The meat industry here [U.S.] could care less if the entire English speaking world goes vegan. The demand in China is big and getting bigger. We could never hope to fill it all but we’re damn sure going to try”.

What is China demanding now more than ever? Equine meat.

Horse Meat Peddlers Busy

While lobbying on the Hill, a U.S. Senator told us that it is hard to make an argument against the United States refusing to compete in the world wide market demand for horse meat. Add to horse meat the strong demand in China for the meat of donkeys and the entire equine meat demand is skyrocketing. It is worth millions if not billions of dollars.

The U.S. Agribusiness wants as much of the equine meat market as it can possibly get. Right now its plan is to eliminate competition in N. America is simply this: kill off one; work with the other.

Canada

The horse meat business in Canada relies heavily on U.S. horses coming across its border to do a brisk business — roughly 60% of all horses slaughtered. A big return of horse slaughter to U.S. soil could for all intents and purposes put an end to horse slaughter in Canada.

Indications are that it would be a similar story with Mexico but with a twist.

Mexico

The U.S. Agribusiness lobby envisions working with Mexican horse slaughter plants, not competing with them.

The EU currently have no horse slaughter plants operating under its jurisdiction in Mexico. This is perfect for what U.S. Agribusiness have in mind.

We were told by a lobbyist for U.S. Agribusiness that they are working on a deal with Mexico to do necessary routine inspections of their horse meat. Mexico would send their horse meat to the U.S. The USDA would “inspect” it (meaning they would test random samples), put their seal on it and send it on its way — for a fee. Horse meat sanctioned by the USDA would be worth millions to both countries. We are told their negotiations are firmly underway.

The proposed location in the U.S. for proposed horse meat inspections and export? Right across the border in Texas. How convenient.

This is why there is movement afoot right now in Texas to open not one but two horse slaughter plants, in a State with a long history of killing horses for their meat and shipping it. Oklahoma is itching to get in the game too we are told and they have thousands of wild horses there to dispose of if the Department of Interior gets what it wants in the 2018 Appropriations Bill.

What must happen for the above to be accomplished? By restoring federal funding to the USDA for horse meat inspections necessary for its export, or in other words NOT returning the defunding provision to next year’s federal budget. Horse advocates want that defunding provision to continue.

Current Status

The U.S. House Appropriations Committee voted not to return the USDA horse meat inspection defunding provision to next year’s spending bill. The U.S. Senate Appropriations Committee voted to keep it. Next up, the full House and full Senate will vote on it.

Take Action

You can see how important continuing the defunding provision for horse meat inspections in next year’s federal budget bill is and how each one of you must keep calling your U.S. Representative and both U.S. Senators, in particular the U.S. House right now as it is divided almost equally.

Horse meat peddlers are licking their chops. Your call could turn the tide in favor of the horses!

Take action by calling your U.S. Representative.

We have this information because we have boots on the ground in Washington thanks to our stellar lobbyists supported by the Horse on the Hill™ Gang. Join today!

Keep a strong voice for our horses where lawmakers are involved. Make a donation. Matching gift reinstated and active for next 24 hours!

The current budget bill that includes the USDA horse meat inspection defunding provision ends September 30, 2017.

Thank you!

 

Donkeys are under threat worldwide

Wild donkeys up for adoption in Hawaii. (Eugene Tanner/The Humane Society of the United States via AP)
Wild donkeys up for adoption in Hawaii. (Eugene Tanner/The Humane Society of the United States via AP)

Originally published by Horse & Man. Go there now »

By Cat Purdy | July 30, 2017

A donkey holocaust is under way around the world. The carnage began in China and now extends to nearly every continent on Earth.

The sought-after ingredient is called donkey hide gelatin, or ejiao (e-gee-ow) in Chinese. Made by boiling the hides of slaughtered donkeys, the resulting gelatin is used in a variety of products – facial creams, powders, and snacks. The largest percentage of these products are sold in China, but many can also be found on Amazon and Ebay.

Like bear bile, donkey hide gelatin has its origins in Traditional Chinese Medicine (TCM) and its use goes back thousands of years. Demand for the product has exploded due to an expanding middle class in China and state-sponsored advertising that promises benefits ranging from anti-aging to virility.

The use of animal products in TCM has a foothold in Chinese culture, but the scale of slaughter in this case is unprecedented. As China is running low on donkeys, it is reaching outside its own borders to meet the demand of 4 to 10 million donkey hides a year. The worldwide population of donkeys was estimated to be about 40 million some years ago. Obviously, this level of slaughter could result in near-extinction for donkeys in a matter of years.

Hides are being sourced from Africa, Asia, the Middle East, and South and Central America, threatening not only donkey populations in those countries but the local people who still depend on them. Some countries see this as an economic opportunity and have set up slaughterhouses to supply hides. Australia is considering exports.

At present, five countries have resorted to banning the export of donkey hides — Niger, Burkina Faso, Pakistan, Mali and Senegal. Black markets are still at work even in these countries, however. In Niger, for example, 65,000 donkeys a year are slaughtered illegally. In addition, the price of a donkey there has risen from $34 to $147, too high for most of the local people who need donkeys to work and to live.

The NSPCA (National Council of SPCAs Africa) said, “Over and above the horrendous cruelty to the donkeys, it is noted that individuals and communities are suffering, as their livelihoods and often their only means of transportation are being taken from them.” Theft and barbaric slaughter methods are on the rise. Donkeys have been skinned alive, bludgeoned to death, and transported for long distances without food, water or rest.

America’s so-called “excess” horses and donkeys currently go to Mexico for slaughter. In all likelihood, the number of donkeys sent to that country will increase, whether by legal or nefarious means, as Mexico is actively trading with China. Continue reading »

* * *

Historically, China has had a long and horrible reputation concerning animal rights. The Western world does not have a lot to brag about in that regard itself, however it is reducing its use of animal products largely in part due to the increase in popularity of veganism and vegetarianism. In the reverse, the Chinese appear to be rapidly increasing in their cruel and deadly use of animals.