Premarin 2019 Year in Review

JANUARY 2019 FDA denies Pfizer Petition asking for new method of assessing Premarin generics The FDA has denied a citizen petition from Pfizer calling on the agency to use the company’s method for assessing sameness in generics for its estrogen drug Premarin (conjugated “equine” estrogens). Pfizer had appealed to the FDA to force sponsors of…

New study damns results of WHI report on Premarin family of drugs

by JANE ALLIN New Study Another new study published September 12, 2017 in the Journal of the American Medical Society (JAMA) has made headlines claiming that HRT is not the villain it was once thought to be. Per the investigators, a statistical review of the results of the damning 2002 WHI study showed that the…

PMU Horses win two awesome new friends

Jane Allin and I, together with you, have been championing the cause of PMU horses for over a decade. PMU horses are mares kept continually pregnant in order to collect their estrogen rich urine to make drugs like Prempro, Premarin and Duavee for the easing of menopausal symptoms. A tragic offshoot of this process are…

Side effects of raising awareness about the Premarin family of drugs and PMU horses

There have been significant side effects to the work we are doing on behalf of the horses affected by the making of the Premarin family of drugs -- Premarin (cream and tablet), Prempro, Premphase and Duavee. BILLBOARD Remember our billboard campaign? It's a simple one. It says, “Warning: Premarin Contains Horse Urine”. We placed these…

Pushing Premarin: Big Pharma, Big Bucks — Part 1

by JANE ALLIN It seems lately that everywhere you look there are ads for Premarin, Premarin Cream and the new kid on the block Duavee*, also derived from Pregnant Mare’s Urine. These sinister advertisements have been materializing repeatedly in numerous US magazines and more recently as a TV ad on iSpot.tv (http://www.ispot.tv/brands/onI/premarin). Pfizer seems intent…

Premarin Horses: How many does it take to make a billion dollars? Part 3

Newest Member of the Premarin Family ― Duavee How will this new drug impact profits and inevitably the PMU mares and their foals? DUAVEE®, the Premarin® ― bazedoxifene combination therapy for the treatment of menopausal symptoms and prevention of postmenopausal osteoporosis in women who have not undergone hysterectomy was FDA-approved in October 2013 amid speculation…

Premarin Horses: How many does it take to make a billion dollars? Part 2

WRITTEN AND RESEARCHED BY JANE ALLIN Part 2 -- Every Figure Tells a Story So let’s get started. Be warned ahead of time that this estimate is very rudimentary and relies heavily on averages and interpolation of information collected from various sources. There are three main estrogens (along with other minor estrogen analogues), collectively referred…

Premarin: The horses, the drugs, the women

THE HORSES Premarin mares are large bred horses such as Belgian—Quarter Horses crosses, prized for their large bladders. For most of their 11-month pregnancies, these horses are confined to stalls so small that they cannot turn around or take more than one step in any direction. The mares must wear rubber urine-collection bags at all…

Big Pharma wins again: FDA approves Aprela under new name

BY JANE ALLIN Despite government shutdown, on October 3, 2013 the FDA approved the dual-acting drug formerly known as Aprela for the treatment of menopausal symptoms and prevention of postmenopausal osteoporosis in women who have not undergone a hysterectomy.[1] It’s new name is fittingly ugly -- DUAVEE® -- for an ugly vile drug that robs…

Aprela® — the making of a new pregnant mare’s urine drug

Part 1 of a Special Report by Jane Allin October 3, 2013 looms as the harbinger of foreboding news for PMU mares and their foals. This is the day that the U.S. Food and Drug Administration (FDA) will make a decision whether or not to approve Ligand Pharmaceutical’s dual-acting drug Aprela® for the treatment of…