Put your thinking cap on and help us help PMU horses

Combating horse cruelty is a full-time job.

However, there is an issue that has a challenge not often faced.

This issue is the mares used and byproducts foals cast off to make the Premarin family of drugs, which now includes Duavee in North America and Duavive in Europe. The challenge is — we can no longer see them.

We can’t see the mares and what happens to them. We can’t see the byproduct foals and what happens to them. But we do know from Premarin’s decades long history in the US and Canada, where the “pee farms” were originally located, how these horses are treated.[1]

Premarin tables. If you look closely you can see a legend in Chinese. Click to enlarge. Google image.
Premarin tables. If you look closely you can see a legend in Chinese. Click to enlarge. Google image.

They are no longer in the US; yes there are some remaining in Manitoba, Canada. However, based on continuing huge sales figures, there are countless thousands of mares located on PMU (pregnant mare’s urine) farms elsewhere operating for example in farflung countries like China.[2]

We don’t know for certain how many horses are being used and how many foals are produced to make these diabolical menopausal horse pee drugs.

Jane Allin crunched the numbers and gave us a reliable insight into that (anything else you hear are inflated numbers with no basis in fact).[3]

The long history of drugs produced with conjugated equine estrogens — taken from the bladders of pregnant mares standing in “pee lines” are dangerous to the patients who take them as well as the horses.

There is however something we can do wherever these horses are. That is raise as much awareness as possible.


We must alert the doctors.

It is amazing the number of doctors who claim they had no idea these drugs are made with pregnant mare’s urine. This has no doubt been easier to conceal from the medical profession since the pharmaceutical industry took the word “equine” out of “conjugated estrogens” in labeling and product descriptions.

We must alert the people who take them.

We have some great tools available that didn’t exist when we began this battle years ago.

Those great tools we refer to are the heightened use and availability of an array of far-reaching social media outlets. If citizens can stage a successful revolution in other countries via Facebook and Twitter then surely we can raise great awareness on behalf of PMU horses and their foals.


Therefore we are asking you to help us get the word out.

"Premarin Vaginal Cream could result in more comfortable sex, uterine cancer, heart disease, heart attacks, stroke, dementia, blood clots or breast cancer."
“Premarin Vaginal Cream could result in more comfortable sex, uterine cancer, heart disease, heart attacks, stroke, dementia, blood clots or breast cancer.” Click to be taken to source article.

Tell us when you see ads for Premarin (particularly Premarin cream which is so prevalent at the moment), Duavee and Duavive products on television or in magazines or promoted by someone well known, or have their names linked to these drugs.

Let us know the date you see them, where you see them, and the product. In the case of television tell us what program you were watching.

We can use this information and select the right social media outlets to expose how these drugs are made and the consequences.

One of our clever volunteers takes her kids to the local Library once a week. She goes to the magazine section and looks through women’s magazines and makes a note of everything she sees and sends it to us with the magazine’s name, the issue date and the page number.

One of our advocates was in a doctor’s office with the usual long wait. She made the most of her time going through every single magazine she could using her phone to take pictures of the front of the magazine and the page the ad was on and sent them to us.

So put your thinking cap on! Do what you can. And share your ideas with us. It will inspire and motivate, and help these dear horses who have no one else to help them but us.

Report television and magazine ads for Premarin, Premarin Cream, Duavee and Duavive using our form »
Make a Donation to Premstoppers »
Learn about Premstoppers »

Sex in the City’s Kim Cattrall teams up with Pfizer to promote Duavee


The Inquistr reports:

What does Kim Cattrall have against women and horses?  Cattrall recently teamed up with Pfizer to promote Duavee, from the Premarin family of drugs, made from the estrogen rich urine of pregnant mares. (Google image).
What does Kim Cattrall have against women and horses? Cattrall recently teamed up with Pfizer to promote Duavee from the Premarin family of drugs, made from the estrogen rich urine of pregnant mares. (Google image).

The 58-year-old Kim Cattrall has teamed up with Pfizer to encourage menopausal women to stay in tune with their bodies and embrace the changes they undergo during menopause. The campaign, called Tune In To Menopause, features stories of Kim Cattrall’s own journey through menopause.

Well, that is part of the story, but not the whole story. Cattrall has put her name to a Duavee sponsored campaign.

A visit to the Tune In To Menopause website shows a picture of Cattrall with the legend “Kim Cattrall is NOT a DUAVEE Patient”.

Well, good for her she is not taking Duavee herself (why not?). But not good for the who knows how many women she will influence and encourage to take Duavee. And how tragic for the countless pregnant mares abused to make this drug and their byproduct foals who end up slaughtered.

It makes you wonder how a woman like this that you might suppose to be intelligent did no research on Duavee, the latest addition to the Premarin family of drugs.

We have of course covered drugs made with pregnant mare’s urine relentlessly for years, i.e. Premarin, Prempro, Premhase and now Duavee.

You will remember that Duavee was originally submitted to the FDA for approval under the name Aprela. The name was switched to Duavee in the final stages and at long last approved by the FDA during the last federal government shutdown after years of failure.

If you are new to this issue, learn more about the Premarin family of drugs including Duavee at our Premstoppers home page which links to a plethora of information.

Jane Allin, a frequent writer on the subject, sums it up this way:

Nothing has been, or ever will be, appealing or beneficial about the PMU industry and the Premarin family of drugs; they are clearly harbingers of death from both sides of the equation“.

If you wish to voice your objections to Cattrall’s promotion of this dangerous drug potentially lethal to women and horses, you may do so via social media:

• Kim Cattrall on Facebook (https://www.facebook.com/KimCattrallOfficial)
• Contact Cattrall on Twitter (@KimCattrall).

Please be respectful.

Say no to Pfizer’s DUAVEE® and yes to safer alternatives
Tell doctors not to prescribe Premarin’s new sister drug Duavee

Premstoppers Home Page

• List of Alternatives

Make a Fonation

Tweet for PMU Horses

Trio of Rescued Premarin Foals. Photo: Vivian Grant Farrell
Trio of Rescued Premarin Foals. Photo: Vivian Grant Farrell

Do you have a Twitter account? Would you like to tweet to help Premarin horses?


— Find a women’s health center or hospital and tweet our Dr Physician letter to them.

— Tweet our Dear Pfizer letter to Pfizer. In the U.S. @Pfizer. In Canada @PfizerCA.


Please do not include anything rude in your tweets. We want to be informational, not confrontational.

Hate tweets send a negative image and the message will be lost or not taken seriously.

Yes, we are thoroughly disgusted with these drugs. But this approach will not help the horses.

Do not flood your tweets with hash tags. You may use #horses #womenshealth #menopause.


If you would like to be part of our Twitter campaign regarding Premarin ads on television and in magazines, please email horsefund@gmail.com.

If you see any of these ads, be sure to let us know.


Those of you who are keeping an eye out for Premarin ads and letting us know where and when you see them, you have done a marvelous job.

The result is that the Premarin television ads you alerted us to are being pulled from rotation. We notice on CBS they are replacing Premarin ads with ones for natural alternatives not using animals.

Good work!


Horses love tweets.

Be sure to follow us @HorseFund. Tuesday’s horse articles are sent to our Twitter feed. And we also tweet and re-tweet breaking news there.


Think the Premarin industry has downsized because of the closing of “pee farms” in North America?

Conjugated equine estrogens are reported as an ingredient of Premarin in the following countries:

Estrogens, conjugated is reported as an ingredient of Premarin in the following countries:

  • Australia
  • Brazil
  • Canada
  • China
  • Costa Rica
  • Ecuador
  • El Salvador
  • Guatemala
  • Honduras
  • Hong Kong
  • India
  • Ireland
  • Japan
  • Lithuania
  • Malaysia
  • Malta
  • Mexico
  • New Zealand
  • Nicaragua
  • Oman
  • Panama
  • Peru
  • Philippines
  • Singapore
  • South Africa
  • Taiwan
  • Thailand
  • United Kingdom
  • United States

Learn more at http://www.horsefund.org/premstoppers-home.php.

Premarin Horses: How many does it take to make a billion dollars? Part 1


Part 1 — Introduction

A billion dollars – lots of zeros.

And keep in mind not just a billion dollars, but a billion dollars or more year after year – this has been the profit margin of the Premarin® family of drugs since Pfizer‘s $68 billion acquisition of rival drug maker Wyeth in October 2009.

Table 1: Premarin Sales
Table 1: Premarin Sales

This collection of contemptible drugs was equally rewarding to Wyeth, one of the very reasons Pfizer lobbied for the takeover despite speculation — a takeover that was to be the biggest merger since AT&T and Bell South combined in a $70 billion deal in March 2006. [1]

Such a merger typically stifles competition and in this case furthers the power over the FDA and similar regulatory bodies. It is no secret that when it comes to NDAs (new drug approvals) and continued support of questionable medications that the FDA is intimidated by Big Pharma and bows to its demands due to financial incentives -– one need only look at the new combination osteo-menopausal therapy DUAVEE®.

More on that later.

Appalling? Certainly, but this is Big Pharma clout which, by nature, instructs the actions of FDA management and their minions.

    “FDA’s own scientists report pattern of intimidation, censorship and scientific fraud that undermines public safety.

    In a truly astonishing survey just released by the Union of Concerned Scientists, the Food and Drug Administration’s own scientists describe the agency as an environment of intimidation, censorship and scientific fraud. A survey of 997 FDA scientists revealed that forty percent feared “retaliation” for voicing safety concerns over prescription drugs in public. Over one-third of the scientists didn’t even feel safe expressing safety concerns inside the agency, behind closed doors!

    Intimidation and censorship have been well documented at the FDA, and this survey adds further weight to the evidence that the FDA has been utterly co-opted by the pharmaceutical industry and now serves Big Pharma’s commercial interests rather than anything resembling a commitment to honest science or public safety.” [2]

If this isn’t sobering enough think about the enormity of its effect on our day-to-day lives and the pill-pushing nation we live in.

Not only is it astounding that year after year Pfizer continues to successfully market and sell these HRT drugs despite their carcinogenic toxicity but even more so the fact that over 90% of the sales take place in the United States.

It is disheartening to think of how many women with access to proven evidence of the damage these drugs are capable of still buying into the propaganda doled out by their physician’s undying loyalty to Big Pharma.

Even more daunting is the realization that there exists an untapped market on the international level ready to be infiltrated by this drug Behemoth’s drive to peddle its deadly wares using deceitful marketing strategies and bribery.

And that untapped market is huge. According to a Bloomberg article “Drug Sales in Emerging Markets to Match US by 2016:

    “China, India, Brazil, Russia are among 16 emerging markets that will make up almost one-third of global drug spending within four years, as newly wealthy people and nations spend more on health care, a report shows . . . .China is leading the growth in these markets.” [3]

No doubt this will have an impact on sales of the Premarin® family of drugs.

But I digress.

Getting back to the reason for this particular report, just how many mares are out there on the pee lines?

The gradual downsizing of the PMU ranches began shortly after the WHI results were released and now stand at approximately 22 farms after the shuttering of a farm in North Dakota in early 2012.

NAERIC (North American Equine Ranching Information Council), the non-profit association of equine ranchers engaged in horse production and management of pregnant mares here in North America claims there are approximately 2,000 broodmares involved in the equine ranching industry. [4] A far cry from 2002 and 2003 where there were as many as 300 PMU farms housing upwards of 50,000 or more mares churning out gallon upon gallon of estrogen-rich urine. [5]

While it is true that immediately following the release of the WHI study, citing the horrors associated with CEE-derived HRT, there was a precipitous drop in sales of Premarin® and Prempro®, much of that market was reclaimed in time via reduced dosage recommendations, aggressive marketing strategies, price increases and the wide availability of these drugs without prescriptions through Internet sales. This is clearly reflected in the continuing profits awarded Pfizer year after year.

Moreover it is common knowledge these days that there is a thriving PMU industry in China and possibly other foreign countries of the world.

This was revealed by The Horse Fund (working as the Int’l Fund for Horses) in March of 2012 wherein according to information procured from an inside source from a company manufacturing conjugated equine estrogens PMU farms had been in operation in Northern China for the last 8 years, now approximately 10 years.

The following May of 2012 a video entitled “Horse urine a profitable industry” aired on BONTVchina which made its way to North America late last year confirming their existence. [6]

While we are aware of the roughly 2,000 mares here in North America it would be interesting to have an indication of the total number of mares required to provide the amount of conjugated equine estrogens (CEEs) for the manufacture of this vile family of carcinogens.

There are several variables required to calculate this number:

  • Concentration of CEEs in pregnant mares urine
  • Change in concentration of CEEs over the collection period
  • Average daily urine output
  • Profits made per annum from the Premarin family of drugs
  • Average cost of a dose of CEEs
  • Average dose of CEEs in the HRT products

There is little transparency in the pharmaceutical industry and facts are hard to come by. Accordingly this assessment was a labor of desire in pursuit of answers which are not forthcoming from the PMU or pharmaceutical industry. Answers which are tenuous and may never be confirmed or denied given the tenacity of Big Pharma and its deceptive character.

Of the list of required information perhaps the most difficult to locate was the concentration of CEEs in pregnant mare’s urine. As much as the Internet provides a wealth of data on many subjects there was little in the way of isolating these concentrations in easy to interpret format. In many cases, specifically those from non-scientific articles and websites, the numbers were ridiculously impractical. Therefore why not go to the source?

Attempts at gleaning any information from Pfizer failed miserably – they were simply not going to divulge any information. So instead why not the new source? China. All it took was one query and the answers were there.
[1] http://www.nytimes.com/2009/01/26/business/26drug.html?pagewanted=all
[2] http://rense.com/general72/fdasown.htm
[3] http://www.bloomberg.com/news/2012-07-12/drug-sales-in-emerging-markets-to-match-u-s-by-2016.html
[4] http://www.naeric.org/about.asp?strNav=4&strBtn=5
[5] http://www.naeric.org/about.asp?strNav=2&strBtn=5
[6] http://www.youtube.com/watch?v=DL5o8c_Fetg

Links to All Parts of this Report

PART 1: Introduction (A billion dollars ― lots of zeros)
PART 2: Every Figure Tells a Story (Calculations and Result)
PART 3: Newest Member of the Premarin Family ― Duavee (Approved by FDA October 2013, originally submitted under the name Aprela)