The checkered history of Pfizer’s Premarin family of drugs

The drugs The name Premarin® spells out in its name what it is made from — PREgant MAres uRINe. Pfizer's Premarin® family of hormone replacement therapy drugs of today includes not only Premarin®, but also similarly manufactured pharmaceuticals — marketed at various times — under the names Prempro®, Premphase®, Provera® and later Aprela® (originally called…

Premarin 2019 Year in Review

JANUARY 2019 FDA denies Pfizer Petition asking for new method of assessing Premarin generics The FDA has denied a citizen petition from Pfizer calling on the agency to use the company’s method for assessing sameness in generics for its estrogen drug Premarin (conjugated “equine” estrogens). Pfizer had appealed to the FDA to force sponsors of…

Duavive —The Yellow Trail of Horse Pee Drugs Crosses the Pond to Europe

by VIVIAN FARRELL and JANE ALLIN The alleged duel-acting horse pee/bazedoxifene drug DUAVIVE—also known as DUAVEE in North America—has now made its way to the EU. Its foundation drug Premarin, which alone and in combination, has been responsible for countless cancer deaths, has now crossed international boundaries. How did this happen? Follow the trail. APRELA…

The Quest for a Generic Premarin – A Bitter Pill to Swallow

BY JANE ALLIN The story of the quest for a generic Premarin is an interesting one – one that dates back to the mid 1980’s when the FDA announced that Premarin was effective in combating the bone loss associated with osteoporosis. To this day an Abbreviated New Drug Application (ANDA) for a generic version has…

Premarin Horses: How many does it take to make a billion dollars? Part 1

WRITTEN AND RESEARCHED BY JANE ALLIN Part 1 -- Introduction A billion dollars – lots of zeros. And keep in mind not just a billion dollars, but a billion dollars or more year after year – this has been the profit margin of the Premarin® family of drugs since Pfizer‘s $68 billion acquisition of rival…

Horse urine a profitable industry in China (video report)

FROM BONTV   We have designated PMU Horses as our topic next year for our month of March campaign. Let us know what you would like to learn more about. Submit ideas and questions in comments. Read posts from our last March for PMU Horses >>

Horse pee reduces breast cancer risk. Say what?

The undying pursuit of trying to find goodness in the devil incarnate BY JANE ALLIN Yet again another study attempting to promote the benefits of conjugated equine estrogen (CEE) derived HRT. Or should I use the “new” acronym – MHT – or menopausal hormone treatment? No doubt more propaganda to distance the facts from the…

Will women have short memories about HRT? Pharma hopes so

As a new generation of women approach menopause, will the HRT lessons of the 1970s and 2000's be lost amid Pharma's marketing again? Martha Rosenberg has been writing intelligently and cohesively about the issues surrounding the Premarin® family of drugs for a good while, and we are very grateful to her. Rosenberg has penned another…

Pfizer pharms and Premarin generics: who’s tapping whose PMUs?

Makers of generic Premarin are looking to move in on Pfizer's contracted PMU ranchers In May Tuesday's Horse reported that the announced job cuts by Pfizer at their estrogen extraction plant in Manitoba is not expected to affect PMU ranchers in Canada and no closures are anticipated. Premarin® and Prempro® are made with the estrogen…

Antivenin that saves life of Florida snake handler made from horses

FRANCES ROBLES reporting for the Miami Herald writes: Snake handler Giselle Hosein was in the middle of her performance Saturday at the Seminole Hard Rock Hotel and Casino near Hollywood, displaying a three-foot Indian cobra also known as “naja naja” when, as she placed the “spectacled” cobra back into its cage, it nipped the palm…